
Is Unipolar Depression the Same Thing as Major Depression?
Key Takeaways: Unipolar depression is major depression: Clinically, the terms unipolar depression and major depression (Major Depressive Disorder, MDD) are used interchangeably to describe the same condition—a persistent depressive state without mania. Core symptoms involve prolonged low mood: People with unipolar/major depression experience persistent sadness, loss of interest in activities,








